There is a known issue where if you try to launch Reports Builder 11g in Windows 7 (32-bit or 64-bit), the Reports Builder will not launch. However, the icon for it appears in the Windows taskbar. Opening it presents the error:

“REP-50125: rwbuilder.conf:java.lang.NullPointerException”

To fix the problem, follow these steps:

1.       Go to C:\Oracle\Middleware\asinst_1\config\FRComponent\frcommon\tools\admin

2.       Make a backup of cauprefs.ora

3.       Look for these entries:

Reports.root_x = “#####”

Reports.root_y = “#####”

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4.       Replace the numbers (represented by #####) with 0 so that they look like this:

Reports.root_x = 0

Reports.root_y = 0

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5.       Save and close the file

6.       Launch Reports Builder. Reports Builder should work successfully.

NOTE: If you open up Reports Builder at a later date and the problem reoccurs, open up cauprefs.ora and modify the same parameters again with the following:

Reports.root_x = 80
Reports.root_y = 30
Reports.root_y = 76

After applying the settings above, Reports Builder should open successfully.

Source: Oracle Support note 1478627.1